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Beside the expression in testes, leukocytes and liver, serpina2 transcripts were also detected in brain, colon, uterus, esophagus, spleen, trachea, kidney and lung.

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AffiliationDepartment of Pathology and Medical BiologyUniversity Medical Center GroningenGRIAC Research InstituteUniversity of GroningenGroningenThe Netherlands.

This section is used to point to information related to entries and found in data collections other than UniProtKB.

We present here the first GWAS on circulating AAT blood levelsOur results confirm that genetic variation in the SERPINA1 gene is a strong determinant of serum AAT levelsFine mapping of SERPINA1 and subsequent stepwise regression analyses further revealed that the associations with common variants in the SERPINA locus could be attributed to rarer variants previously identified to be causally linked with AAT deficiency.

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