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There are no systematically collected data that specifically address the switch from buprenorphine or methadone to REVIAhoweverreview of postmarketing case reports have indicated that some patients may experience severe manifestations of precipitated withdrawal when being switched from opioid agonist therapy to opioid antagonist therapysee WARNINGSPatients transitioning from buprenorphine or methadone may be vulnerable to precipitation of withdrawal symptoms for as long as 2 weeksHealthcare providers should be prepared to manage withdrawal symptomatically with non-opioid medications.

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