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The client diagnosed with chronic obstructive pulmonary disease is prescribed methylprednisolone solu-medrol , a glucocorticoid, ivp.

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When treatment is to be withdrawn after prolonged and intensive therapythe dose should be reduced gradually.

MEDROL Tabletslike prednisolone and other adrenocortical steroids is a potent therapeutic agent influencing the biochemical behavior of mostif not alltissues of the bodyBecause this anti-inflammatory steroid manifests little sodium-retaining activitythe usual early sign of cortisone or hydrocortisone overdosageieincrease in body weight due to fluid retentionis not a reliable index of overdosageHencerecommended dose levels should not be exceededand all animal patients receiving MEDROL should be under close medical supervisionAll precautions pertinent to the use of prednisolone apply to methylprednisoloneMoreoverthe veterinarian should endeavor to keep informed of current studies with MEDROL as they are reported in the veterinary literature.

Frequency not reportedBradycardiacardiac arrestcardiac arrhythmiascardiac enlargementcirculatory collapsecongestive heart failurefat embolismhypertensionhypertrophic cardiomyopathy in premature infantsmyocardial rupture following recent myocardial infarctionsyncopetachycardiathromboembolismthrombophlebitisvasculitisedemahypotensionRef]

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