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Ezetimibe represents the first cholesterol-lowering drug of a new class that inhibits cholesterol absorption from the small intestineIt can be used as monotherapy for primary hypercholesterolemia but most likely will be used in combination therapy with statins in which it results in incremental lowering of total and LDL cholesterol1234It can also be used as part of therapy for homozygous familial hypercholesterolemia and homozygous sitosterolemiaIt does not increase the incidence of myopathy or rhabdomyolysis when administered with HMG-CoA reductase inhibitorsstatins

Take Zetia exactly as it was prescribed for youFollow all directions on your prescription labelDo not take this medicine in larger or smaller amounts or for longer than recommended.

Fibrates may increase cholesterol excretion into the bileleading to cholelithiasisIn a preclinical study in dogsezetimibe increased cholesterol in the gallbladder bilesee Nonclinical ToxicologyCoadministration of ZETIA with fibrates other than fenofibrate is not recommended until use in patients is adequately studied.

This is not a list of all drugs or health problems that interact with Zetiaezetimibe

This summarizes the most important information about ZETIAIf you would like more informationtalk with your doctorYou can ask your pharmacist or doctor for information about ZETIA that is written for health professionals.

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