Nizoral no debe ser administrado un pacientes con enfermedad heptica aguda o crnica o con hipersensibilidad conocida a los componentes de la frmula.
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Avoid taking antacidsstomach acid reducersor medicines to treat stomach ulcer or gastroesophageal reflux diseaseAxidNexiumPepcidPrevacid PrilosecsucralfateTagametZantacand othersThese medications can make it harder for your body to absorb Nizoral.
Severe itchingburningor irritation where the medicine is appliedoily or dry scalpmild hair lossrednesspainor oozing of treated skin areasor eye rednessswellingor irritation.
Co-administration of ketoconazole with potent CYP3A4 enzyme inducers is not recommended.
Ketoconazole is cis-1-acetyl-4422,4-dichlorophenyl21H-imidazol-1-ylmethyl1,3-dioxolan4-yl]methoxy]phenyl]piperazine and has the following structural formula:
Serious hepatotoxicityincluding cases with a fatal outcome or requiring liver transplantationhas occurred with the use of oral ketoconazoleSome patients had no obvious risk factors for liver diseaseSerious hepatotoxicity was reported both by patients receiving high doses for short treatment durations and by patients receiving low doses for long durations.
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